Reset Your Brain's Reward System and Raise Your Dopamine Baseline.

Low dopamine levels drive cognitive decline, depression, anxiety & ADHD.

[PMID: 10232292, 30446950, 18458204, 19738093, 15236398, 16402097 2736402, 11291999, 8029265, 16163534, 24795692, 19738093]

Dopamine shapes far more of our daily life than most people realize. It's not just a chemical tied to pleasure: it's the reason you feel pulled toward a goal in the first place. When you want something, whether that's finishing a project, hitting a personal best at the gym, or just getting through your to do list, dopamine is what creates that pull.

IT DOESN'T REWARD YOU AFTER YOU SUCCEED,

IT DRIVES YOU BEFORE YOU EVEN START!

building the anticipation that makes the goal feel worth chasing. That's why a healthy dopamine system makes life feel purposeful and exciting, while a damaged one leaves you flat, unmotivated, and stuck watching other people move forward while you stay in place.

Imagine drinking a cold coke after a few hours in the sun.

Without you noticing your brain just released a lot Dopamine.

a single tiny chemical in the brain that's behind all of these small thrills.

The brain does not release it when you are done and satisfied. It releases it when something might pay off, and when chasing is worth the cost. That is why a short video beats a long task.

If you want more motivation, better focus, higher cognitive function, more creativity and stronger discipline you need high dopamine production.

The chemical pathway

Phenylalanine -> tyrosine -> L-DOPA -> dopamine -> norepinephrine -> epinephrine.

The most important steps here are

Tyrosine -> L-DOPA -> Dopamine.

Those are the rate limiting steps in the chain and often those are the main bottleneck in dopamine production, focusing on optimizing those would have the most effective impact.

High dopamine = High cognitive function and creativity

"The acceleration of word learning after L-dopa intake complies with our working hypothesis that during massed training there is a trade-off between stimulus repetition and dopaminergic encoding of stimulus."

In this study, dopamine agonists and L-DOPA increased creativity in Parkinson patients.

Tyrosine

the amino acid Tyrosine is the building block for Dopamine. When it's low our cells simply can't produce enough dopamine.

High tyrosine intake is another approach that together with bromantane can enhance dopamine production. In this study 23 US soldiers took tyrosine(100mg/kg)

In this study 23 US soldiers took tyrosine(100mg/kg)

The results: Improved pattern recognition, clear thinking and mood. less fatigue, coldness, anxiety, muscular discomfort and headaches.

Supporting Tyrosine conversion to L-DOPA and then to dopamine is

THE MOST!

effective approach for strong dopamine tone.

In this study Bromantane increases the expression of genes responsible for producing Tyrosine hydrolase DOPA decarboxylase.

In the initial stage of the drug action, the dopaminergic effects are related to an increase in the dopamine release" "This leads to a conclusion that the pharmacological activity of bromantane is related to activation of de novo synthesis of tyrosine hydrolase and DOPA-decarboxylase"

Supplementing Bromantane is effective approach to enhance dopamine production at the genetic level.

If you're in Europe it's easy to get, If you're in the US try

https://www.realpeptides.co/products/bromantane/ref/oxidativestate

They have 100mg bromantane in each tablet.

Sunlight and Dopamine

Another crucial factor for dopamine production in the brain(which is where it matters the most) is exposing your eye balls to the sun

This study shows how light activates Tyrosine hydroxylase in retinal neurons, the retina isn't merely "connected" to the brainת it literally is brain tissue, they set the tone of dopamine production.

Staring all day on blue screens without going outside looking at the sun and sky is very effective for nuking your dopamine levles.

Stop doom scrolling

Doom scrolling creates a vicious loop, you get cheap dopamine at first but as time goes by it nukes dopamine synthesis, making you desperate for more dopamine so you doom scroll even more.

This study explored that link.

"we find that a higher proportion of social app interactions correlates with lower dopamine synthesis capacity"

FOCUS ON SLEEP

Sleep deprivation lowers dopamine synthesis.

Our circadian rhythms control dopamine levels, going to sleep in the same time every night and sleeping for 7-9 hours is very effective for suppporting dopamine synthesis.

Gut inflammation nukes dopamine

Gut inflammation driven by bacterial dysbiosis or leaky gut weakens the gut barrier and increases production of inflammatory mediators like serotonin,histamine,cytokins,prostaglnadins,leukotriens.

Weak gut barrier driven by inflammation allow those inflammatory mediators and bacterial endotoxins(LPS) to penetrate and enter into the bloodstreams, once they are there they further push the infalmmatory response, drive cortisol production and inhibit dopamine production.

Healthy gut = More dopamine

Here's a few effective compounds:

BPC157

A protective protein derived from human gastric juice.

It has the ability to inhibit inflammation, strengthen the gut barrier, heal damaged tissues, improve blood flow and angiogenesis,.

[PMID: 18818478, 18649140, 23220707, 38583442, 29358856, 30622376, 39325560, 20190676, 20225319, 39861766, 14554208, 10672992

For example in this study BPC157 repaired gut tissue more effectively than a few drugs, It's a miracle drug for the gut barrier..

Take 1000mcg daily(2 caps).

Best source with PDF labs for every batch.

https://www.realpeptides.co/products/bpc-157-capsules/ref/oxidativestate

Beef gelatin

The amino acids glycine and proline that in it are crucial for gut mucus production(MUC2), both are anti-inflammatory and enhance the gut barrier.

Niacinamide

Beyond raisin the NAD/NADH ratio, Niacinamide can heal the gut barrier and improve gut microbime(B1 also).

Our gut barrier requires a lot of energy to maintain, oxidative stress as low NAD/NADH ratio makes the gut barrier weak as fuck.

Sugar

Sugar itself increases dopamine, while also providing your barin the energy it needs to maintain dopamine production.

Caffeine

Caffeine doesn't make your brain release more dopamine. Instead, it makes the dopamine you already have work harder. Here's how: your brain also makes a chemical called adenosine, and adenosine's job is to slow things down and make you feel sleepy. Caffeine blocks the spots where adenosine would normally attach itself, so adenosine can't do its job. With adenosine out of the way, dopamine sticks around longer and has more room to act, which is why a cup of coffee can sharpen your focus and lift your mood.

Some research suggests that with regular use, caffeine can even increase the number of dopamine receptors in certain parts of the brain, giving dopamine more places to latch on. That helps explain why coffee drinkers often feel more motivated and alert, especially since the brain also needs raw materials to build dopamine in the first place, and caffeine seems to work well alongside that process.

Do not betray yourself!

Every time you promise yourself something, like working out or going to bed early, and then you don't follow through, you shut down your dopamine production and damage your own motivation system. You teach yourself that you can't be trusted, that the things you expect to happen just don't happen. That drags down your baseline dopamine levels and traps you in a negative loop: one that makes you not want to work out or sleep early in the first place.

If you decide to do something: follow through.

Oxidative State.